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Department of Health and Human Services grants

407 open opportunities right now, 521 forecasted. Who can apply, what closes next, and where HHS grant money went last year.

407open opportunities now
521forecasted
35closing in 30 days
$600,000median award ceiling listed
$64.4 billionproject grants and cooperative agreements, last 12 months

What the data says

Department of Health and Human Services has 407 open opportunities on Grants.gov right now and 521 forecasted; 35 close in the next 30 days.

Who can apply: 86% of listings are open to colleges and universities, 83% to nonprofits, 86% to state, local or tribal governments; 8% have no listed restriction. 79% describe eligibility only in the listing text, so check those directly.

The most common funding category is Health (92% of listings).

Over the last 12 months, HHS obligated $64.4 billion in project grants and cooperative agreements. The largest program was Head Start (93.600), at 18% of that total.

Recipients in California received the most ($8.1 billion), followed by New York.

Open and forecasted, soonest deadline first

Each links to the official Grants.gov listing.

Development and Testing of a Multi-use Frameworks Playbook for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U01 Clinical Trial Not Allowed)National Institutes of Health · closes 2026-10-09 · up to $300,000Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Clinical Centers (U01 Clinical Trial Required)National Institutes of Health · closes 2026-10-09 · up to $1.0 millionOptimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Research Coordinating Center (U24 Clinical Trial Not Allowed)National Institutes of Health · closes 2026-10-09Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (R01 Clinical Trial Required)National Institutes of Health · closes 2026-10-11NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed)National Institutes of Health · closes 2026-10-14NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Required)National Institutes of Health · closes 2026-10-14Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)National Institutes of Health · closes 2026-10-14 · up to $250,000Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)National Institutes of Health · closes 2026-10-14Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)National Institutes of Health · closes 2026-10-14Maximizing the Scientific Value of Data Generated by the Environmental influences on Child Health Outcomes (ECHO) Program: Dissertation Grant (R36 - Clinical Trial Not Allowed)National Institutes of Health · closes 2026-10-15Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI) (R01 Clinical Trial Optional)National Institutes of Health · closes 2026-10-15CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed)National Institutes of Health · closes 2026-10-16 · up to $300,000

Who can apply

Public and state-controlled institutions of higher education86% · 799
Private institutions of higher education85% · 786
Federally recognized Native American tribal governments84% · 777
Nonprofits with 501(c)(3) status (other than higher education)83% · 774
Native American tribal organizations (other than federally recognized tribal governments)82% · 761
State governments82% · 758

Funding categories

Health92% · 852
Education13% · 120
Food and Nutrition9% · 82
Income Security and Social Services7% · 69
Consumer Protection5% · 48
Agriculture5% · 47

Posting offices

National Institutes of Health73% · 676
Food and Drug Administration6% · 54
Centers for Disease Control and Prevention - ERA6% · 52
Health Resources and Services Administration5% · 49
Indian Health Service2% · 18
Administration for Community Living2% · 15

Where the money went

Project grants and cooperative agreements, 2025-10-01 to 2026-09-30.

Largest programs

Head StartALN 93.600 · $11.5 billion
Health Center ProgramALN 93.224 · $5.3 billion
Allergy and Infectious Diseases ResearchALN 93.855 · $4.0 billion
Aging ResearchALN 93.866 · $3.9 billion
Biomedical Research and Research TrainingALN 93.859 · $3.0 billion
Cardiovascular Diseases ResearchALN 93.837 · $3.0 billion

Top recipient states

California$8.1 billion · 13%
New York$5.7 billion · 9%
Texas$4.2 billion · 7%
Massachusetts$3.8 billion · 6%
Pennsylvania$3.2 billion · 5%
Florida$2.3 billion · 4%

Largest recipients

the Johns Hopkins University$847.8 million · 1%
Regents of the University of California, San Francisco, the$843.5 million · 1%
Regents of the University of Michigan$752.6 million · 1%
Trustees of the University of Pennsylvania, the$734.6 million · 1%
Washington University, the$716.1 million · 1%

Spending by sub-agency

National Institutes of Health$33.8 billion · 52%
Administration for Children and Families$14.8 billion · 23%
Health Resources and Services Administration$12.0 billion · 19%
Substance Abuse and Mental Health Services Administration$3.5 billion · 5%
Food and Drug Administration$214.5 million · 0%
Agency for Healthcare Research and Quality$42.0 million · 0%
Centers for Disease Control and Prevention$923,289 · 0%
Office of Assistant Secretary for Preparedness and Response$828,824 · 0%

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Sources: open and forecasted opportunities from Grants.gov (public domain), as indexed by Aeonis Grants right now. Federal spending from USAspending.gov (public domain) for 2025-10-01 to 2026-09-30: obligations on project grants and cooperative agreements, by awarding agency, assistance listing, recipient state and recipient. Not affiliated with or endorsed by Grants.gov, USAspending.gov or any agency. Always confirm eligibility and deadlines in the official listing.

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